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STD Testing in Florence, South Carolina

5 STD and HIV testing locations in Florence, including 2 that list free testing.

Verify with the clinic before visiting. Hours, services, fees and appointment rules change. Call ahead to confirm. This directory is for information only and is not medical advice. In an emergency, call 911.

HopeHealth Incorporated – Medical Plaza

360 N Irby St, Florence, SC 29501 · (843) 667-9414
Free testing listedSliding scaleChlamydiaGonorrheaSyphilisHIVRapid HIVHepatitis CHepatitis B
Mon 8:00am – 8:00pm; Tue 8:00am – 8:00pm; Wed 8:00am – 8:00pm; Thu 8:00am – 8:00pm; Fri 8:00am – 8:00pm; Sat 8:00am – 8:00pm

HopeHealth Incorporated – Francis Marion Clinic

121 S Evander Dr, Florence, SC 29506 · (843) 432-2935
Free testing listedSliding scaleChlamydiaGonorrheaSyphilisHIVRapid HIVHepatitis C
Mon 8:30am – 5:00pm; Tue 8:30am – 5:00pm; Wed 8:30am – 5:00pm; Thu 8:30am – 5:00pm; Fri 8:30am – 5:00pm

Genesis Health Care Incorporated – Florence

1523 Heritage Ln, Florence, SC 29505 · (843) 673-0900
Sliding scaleChlamydiaGonorrheaSyphilisHIV
Mon 8:00am – 5:00pm; Tue 8:00am – 5:00pm; Wed 8:00am – 5:00pm; Thu 8:00am – 5:00pm; Fri 8:00am – 12:00pm

Regional Health and Testing Center

376 W Palmetto St, Florence, SC 29501 · (843) 799-0642
ChlamydiaGonorrheaSyphilisHerpesHIV
Mon 8:00am – 5:00pm; Tue 8:00am – 5:00pm; Wed 8:00am – 5:00pm; Thu 8:00am – 5:00pm; Fri 8:00am – 5:00pm

South Carolina Department of Public Health – Florence County Public Health Department

145 E Cheves St, Florence, SC 29506 · (843) 661-4835
Sliding scaleChlamydiaGonorrheaSyphilisHIVHepatitis C
Mon 8:30am – 5:00pm; Tue 8:30am – 5:00pm; Wed 8:30am – 5:00pm; Thu 8:30am – 5:00pm; Fri 8:30am – 5:00pm

Community health centers in Florence

These federally funded health centers (HRSA) offer primary care, usually on a sliding fee scale. Their STD testing services are not confirmed in our data. Call to confirm STD testing.

HopeHealth Celebration Blvd

1362 Celebration Blvd, Florence, SC 29501 · (843) 667-9414
Hopehealth INC · Community health center (HRSA). Call to confirm STD testing.

HopeHealth Community Center

301 N Dargan St, Florence, SC 29506 · (843) 667-9414
Hopehealth INC · Community health center (HRSA). Call to confirm STD testing.

HopeHealth ECP Florence

1530 McClure Ct, Florence, SC 29505 · (843) 667-9414
Hopehealth INC · Community health center (HRSA). Call to confirm STD testing.

HopeHealth Pine Needles

3380 Pine Needles Rd, Florence, SC 29501 · (843) 432-3670
Hopehealth INC · Community health center (HRSA). Call to confirm STD testing.

HopeHealth Second Loop Rd

1920 2nd Loop Rd, Florence, SC 29501 · (843) 432-3700
Hopehealth INC · Community health center (HRSA). Call to confirm STD testing.

HopeHealth at the Manor

2100 Twin Church Rd, Florence, SC 29501 · (843) 667-9414
Hopehealth INC · Community health center (HRSA). Call to confirm STD testing.

HopeHealth, Inc.

600 E Palmetto St, Florence, SC 29506 · (843) 667-9414
Hopehealth INC · Community health center (HRSA). Call to confirm STD testing.

Frequently asked questions

Where can I get STD testing in Florence, SC?

This page lists 5 STD/HIV testing locations in Florence, SC from the CDC NPIN directory, plus 7 community health centers that may offer testing. Call ahead to confirm services and hours.

Is there free STD testing in Florence, SC?

2 of the 5 listed locations say they offer free STI and/or HIV testing. Eligibility can depend on age, income or residency. Many health departments and community health centers also use sliding-scale fees.

Do I need an appointment?

1 locations here say no appointment is required. Others may need an appointment. Call before you go.

Can I get a rapid HIV test?

2 locations here list rapid HIV testing, which usually gives results during the same visit.

Which tests should I ask for?

Common tests include chlamydia, gonorrhea, syphilis, HIV and sometimes herpes or hepatitis. Which ones you need depends on your situation, so a clinician can help you decide. CDC recommends everyone ages 13 to 64 get tested for HIV at least once.

Is STD testing confidential?

Health care providers must keep your health information private. Some public health clinics offer anonymous HIV testing. Ask the clinic about their privacy policy.

Data: CDC NPIN and HRSA. Page built 2026-11-03.