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Sanford Health – Sanford Infectious Disease and Travel Medicine Clinic

STD/STI testing location in Sioux Falls, South Dakota.

Verify with the clinic before visiting. Hours, services, fees and appointment rules change. Call ahead to confirm. This directory is for information only and is not medical advice. In an emergency, call 911.

Address: 1420 W 22nd ST, Ste 401, Sioux Falls, SD 57105
Get directions

Phone: (605) 328-8120

Website: https://www.sanfordhealth.org/locations/sanford-infectious-disease-and

Tests listed

Cost and payment

Free Mpox Vaccine, Medicaid Accepted, Fee, Insurance Accepted.

Hours

Monday8:00am – 5:00pm
Tuesday8:00am – 5:00pm
Wednesday8:00am – 5:00pm
Thursday8:00am – 5:00pm
Friday8:00am – 12:00pm

Appointment required: Yes

Other services

STI treatment, PrEP (HIV prevention medicine).

Languages: American Sign Language, Chinese, English, French, Haitian Creole, Interpretation Services Available for Non-English Languages, Portuguese, Spanish, Tagalog, Vietnamese

Type: Clinic

Source: CDC NPIN listing. Last updated by source: 2026-04-15. Page built 2026-11-03.

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