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River Valley Health – Knox County 5th Ave Health Center
STD/STI testing location in Knoxville, Tennessee.
Verify with the clinic before visiting. Hours, services, fees and appointment rules change. Call ahead to confirm. This directory is for information only and is not medical advice. In an emergency, call 911.
Address: 538 W 5th Ave, Knoxville, TN 37917
Get directions
Phone: (865) 525-2104
Website: https://www.cherokeehealth.com/locations/5th-avenue-knoxville-tn
Tests listed
- Chlamydia Test
- Conventional HIV Test
- Gonorrhea Test
- Hepatitis A Test
- Hepatitis B Test
- Hepatitis C Test
- Herpes Test
- Rapid HIV Test
- Syphilis Test
- TB Test
Cost and payment
Free Mpox Vaccine, Medicaid Accepted, Sliding Scale, PrEP for uninsured, Fee, Insurance Accepted.
Hours
| Monday | 8:00am – 5:00pm |
| Tuesday | 8:00am – 5:00pm |
| Wednesday | 8:00am – 5:00pm |
| Thursday | 8:00am – 5:00pm |
| Friday | 8:00am – 5:00pm |
Appointment required: Yes
Other services
STI treatment, PrEP (HIV prevention medicine).
Languages: English, Interpretation Services Available for Non-English Languages
Type: Federally Qualified Health Center (FQHC)
Source: CDC NPIN listing. Last updated by source: 2026-06-25. Page built 2026-11-03.